Nematicidal activities of different plants viz., Amaranthus viridis, Chenopodium album, Solanum nigrum, Carica papaya and Euphorbia hirta have been evaluated against root-knot nematodes. Plants were collected from different areas of Karachi. Aqueous extracts (2, 6 and 10%) of these five plant species were made for the experiment. All selected plant species inhibited egg hatching and caused larval mortality. Maximum reduction (24.3%) in egg hatching was recorded in C. album stem extract at 2% concentration. The minimum reduction (0.33%) was observed in the leaf extract of A. viridis at 10% concentration after 48 hours of exposure time. In larval mortality test, maximum larval mortality (33%) was recorded in C. album leaf extract at 10% concentration while minimum larval mortality (0.66%) was noted in Solanum nigrum at 2% concentration in leaves and stem extracts after 72 hours of exposure time as compared to control.